Works with

Mouse

GENE symbol

Tgfb1

NCBI GENE nr

21803

Ab raised in

Rabbit

Protein nr

P01137

KDa

42 kDa

Omim nr

6755775

Quantity per ml

1 mg/ml

Ncbi nr

NP_035707

French translation

anticorps

Type

Polyclonal

Vial with antibody

Lyophilized

Source

Mus musculus

Antibodie's label

unlabelled serum

Immuno application

ELISA, Western Blot

Antigene name

transforming growth factor, beta 1

Gene names

Tgfb1, TGF-beta1, TGFbeta1, Tgfb, Tgfb-1

Purity

Antibody is purified by protein A chromatography method.

Antigen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse Tgfb1.

Suspention, pH, azide

Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.

Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Keep at

For short periods of storage (days) store at 4 grades C. For longer periods of storage, store Tgfb1 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.

Antibody advice

Tgfb1 antibody can be used for detection of Tgfb1 by ELISA at 1:62500. Tgfb1 antibody can be used for detection of Tgfb1 by western blot at 1.25 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Gene info

Tgfb1 is a multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodelling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.