NCBI GENE nr
Ab raised in
ELISA, Western Blot
transforming growth factor, beta 1
Suspention, pH, azide
Ascitic fluid containing 0.03% sodium azide.
TGFBTGF-beta-1, CED, LAP, DPD1, TGFB, TGFbeta
Ni-NTA purified truncated recombinant TGFbeta1 expressed in E. Coli strain BL21 (DE3).
Western Blot:1:500 - 1:2,000 ELISA:Propose dilution 1:10,000.Determining optimal working dilutions by titration test.
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
TGF beta1 monoclonal antibody can be stored at -20 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
TGF beta(transforming growth factor beta), with 390-amino acid protein (about 43 kDa), is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2,and beta3,are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression.TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage.