Gene name

N/A

Gene name synonims

N/A

Concentration

N/A

Immunoglobulin isotype

IgG

Species reactivity

Human

Alternative name4

TGFBR1

French translation

anticorps

Category

Antibodies

Clonality

Polyclonal

Conjugation

Biotinylated

Tested for:

Western Blot (WB)

Clone

Polyclonal antibody

Host organism

Host: Goat; Source: Human

Purification method

Affinity Purified by immunoaffinity chromatography.

Other gene names

TGFBR1; TGFBR1; AAT5; ALK5; SKR4; ALK-5; LDS1A; LDS2A; TGFR-1; ACVRLK4; N/A

Specificity and cross-reactivity

Recognizes human TGF-beta RI. Species sequence homology: rat (93%), porcine and bovine (91%), mouse (90%).

Form/Appearance

Supplied as a lyophilized powder from PBS, 50ug/1ug BSA. Labeled with Biotin. Reconstitute with sterile TBS, pH 7.3, 20mM Trizma, 150mM sodium chloride, 0.1% BSA.

Alternative name2

TGFBR1, ID (TGF-beta Receptor Type I, TGFR-1, Transforming Growth Factor-beta Receptor Type I, TGF-beta Type I Receptor, TbetaR-I, TGF-beta Type I Receptor, Activin Receptor-like Kinase 5, ALK-5, TGF beta Receptor I) (Biotin)

Alternative name3

TGFBR1, ID (TGF-beta Receptor Type I, TGFR-1, Transforming Growth Factor-beta Receptor Type I, TGF-beta Type I Receptor, TbetaR-I, TGF-beta Type I Receptor, Activin Receptor-like Kinase 5, ALK-5, TGF beta Receptor I) (Biotin)

Alternative name1

Anti-TGFBR1, ID (TGF-beta Receptor Type I, TGFR-1, Transforming Growth Factor-beta Receptor Type I, TGF-beta Type I Receptor, TbetaR-I, TGF-beta Type I Receptor, Activin Receptor-like Kinase 5, ALK-5, TGF beta Receptor I) (Biotin)

Alternative name5

Anti -TGFBR1, ID (TGF-beta Receptor Type I, TGFR-1, Transforming Growth Factor-beta Receptor Type I, TGF-beta Type I Receptor, TbetaR-I, TGF-beta Type I Receptor, Activin Receptor-like Kinase 5, ALK-5, TGF beta Receptor I) (Biotin)

Advisory

In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Properties

If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.

Storage and shipping

Lyophilized powder may be stored productone should be stored at -20 degrees Celsius.. Stable for 12 months productone should be stored at -20 degrees Celsius.. Reconstitute with sterile TBS, 0.01% BSA. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, productone should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Description

productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.

Other names

TGF-beta receptor type-1 isoform 2; TGF-beta receptor type-1; TGF-beta receptor type-1; tbetaR-I; OTTHUMP00000021783; TGF-beta receptor type I; TGF-beta type I receptor; activin receptor-like kinase 5; transforming growth factor beta receptor I; serine/threonine-protein kinase receptor R4; activin A receptor type II-like kinase, 53kD; activin A receptor type II-like kinase, 53kDa; transforming growth factor-beta receptor type I; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD); transforming growth factor, beta receptor 1; Activin receptor-like kinase 5; ALK-5; Serine/threonine-protein kinase receptor R4; SKR4; TGF-beta type I receptor; Transforming growth factor-beta receptor type I

Additional description

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.