TGF beta 1 Antibody, ALEXA FLUOR 488

7040

None

Human

P01137

Secreted

anticorps

IF(IHC-P)

Polyclonal

Unmodified

TGF beta 1

499nm/519nm

100-150/390

1ug per 1ul

Alexa Fluor

ALEXA FLUOR® 488

Polyclonal antibody

IF(IHC-P)(1:50-200)

Purified by Protein A.

Conjugated Primary Antibodies

Rabbit (Oryctolagus cuniculus)

Anti-TGF beta 1 PAb ALEXA FLUOR 488

This is a highly specific antibody against TGF beta 1.

TGF beta 1 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

CED; LAP; DPD1; TGFB; TGFbeta; Transforming growth factor beta-1; TGF-beta-1; TGFB1

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TGF beta 1/LAP

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-TGF beta 1 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 cells.