Target of this antibody:
Form of antibody:
Concentration of antibody:
Clonality of antibody:
This antibody has been succesfully tested for use in following methods:
This antibody reacts with:
Human, mouse, rat
Shelf time: 12 months in temp.: -20 deg.C
How to handle this antibody:
The antibody solution should be gently mixed before use.
Synthetic peptide mapping to the C-terminus of human TAB1
Alternative names of antibody target:
ANTI TAB1 ,TAK1 , TGF beta activated kinase 1 , MGC57664 , MAP3K7IP1
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Formulation of this antibody:
100 µg (0.5 mg/ml) peptide affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Western blotting (1-4 µg/ml). The optimal concentrations should be determined individually. The antibody recognizes TAB1 in samples from human, mouse and rat origins. BaF3 cells can be used as positive controls. A ~60 kDa band should be detected.
TAB1 (TAK1 binding protein 1) is an adaptor protein that can activate TAK1 in vivo throμgh phosphorylation of TAK1, a mitogen-activated protein kinase kinase kinase. Once activated TAK1 phosphorylates MAPK kinase MKK4 and MKK3/6, which activate p38 MAPK and JNK, respectively.