Antibody host:

Rabbit

Form of antibody:

Liquid

Target of this antibody:

TGF-β1

Shipping conditions:

gel pack

Concentration of antibody:

0.5 mg/ml

French translation

anticorps

Isotype:

Rabbit IgG

Clonality of antibody:

Polyclonal

This antibody has been succesfully tested for use in following methods:

Western blot

Purification method:

Affinity purified

This antibody reacts with:

Human, mouse, rat, porcine

Storage information:

Shelf time: 12 months in temp.: -20 deg.C

Alternative names of antibody target:

Transforming growth factor beta-1, TGF-beta-1

How to handle this antibody:

The antibody solution should be gently mixed before use.

Immunogene sequence:

Synthetic peptide surrounding amino acid 374 of human TGF-β1.

Properties

If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Formulation of this antibody:

100 µg (0.5 mg/ml) affinity purified, rabbit anti-TGF-β1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.

Recommended usage:

The antibody can be used for Western blot analysis (0.5-4 µg/ml) and immunohistochemistry (10-20 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide (Cat.# 5559BP-50) is available separately.

Background information:

TGF-β(transforming growth factor-beta) is a family of multifunctional proteins. TGF-β was originally identified for its ability to induce the growth of normal rodent fibroblast in soft agar. It is now known that TGF-β is a potent growth inhibitor of many normal and transformed cell lines. It regulates normal cell growth, development and tissue remodeling following injury. TGF-β is produced as latent high molecular weight complexes. The activation of latent TGF-β is an important step in the regulation of its action.