Gene ID

7046

Swiss-Prot No.

P36897

MW (kDa)

55 kDa

Source

Rabbit

NCBI Gene Symbol

TGFBR1

Reactivity

H, M, R

Concentration

1 mg/ml

Target Modification

Phospho

Immunogen Range

131-180

Applications

IF ELISA

Unigene No.

Hs.494622

French translation

anticorps

Clonality

Polyclonal

OMIM No.

190181/608967/609192

Modification Sites

H:S165, M:S165, R:S163

Storage / Stability

Stable at -20°C for at least 1 year.

Physical Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Specificity

TGF beta Receptor I (Phospho-Ser165) Antibody detects endogenous levels of TGF beta Receptor I only when phosphorylated at Ser165.

Immunogen

The antiserum was produced against synthesized peptide derived from human TGF beta Receptor I around the phosphorylation site of Ser165.

Properties

If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Synonyms

ADRB2; ALK-5; Activin receptor-like kinase 5; ESK2; SKR4; TGF-beta receptor type I precursor; TGF-beta type I receptor; TGF-betaR1; TGFR-1; TGFR1; kinase TGF-beta-R1; receptor R4

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.