Reactivity
H, M
Gene ID
7048
Swiss-Prot No.
P37173
MW (kDa)
64 kDa
Source
Rabbit
NCBI Gene Symbol
TGFBR2
Concentration
1 mg/ml
Target Modification
Phospho
Immunogen Range
191-240
French translation
anticorps
Applications
IHC ELISA
Clonality
Polyclonal
Modification Sites
H:S225 M:S250
Unigene No.
Hs.604277/Hs.82028
OMIM No.
133239/190182/610168/610380
Storage / Stability
Stable at -20°C for at least 1 year.
Synonyms
TGF-beta receptor type II; TGFR-2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II; TbetaR-II
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Properties
If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Specificity
TGF beta Receptor II (Phospho-Ser225/250) Antibody detects endogenous levels of TGF beta Receptor II only when phosphorylated at Ser225/250.
Immunogen
The antiserum was produced against synthesized peptide derived from human TGF beta Receptor II around the phosphorylation site of Ser225/250.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.