Gene ID
7046
Swiss-Prot No.
P36897
MW (kDa)
55 kDa
Source
Rabbit
NCBI Gene Symbol
TGFBR1
Reactivity
H, M, R
Concentration
1 mg/ml
Target Modification
Phospho
Immunogen Range
131-180
Applications
IF ELISA
Unigene No.
Hs.494622
French translation
anticorps
Clonality
Polyclonal
OMIM No.
190181/608967/609192
Modification Sites
H:S165, M:S165, R:S163
Storage / Stability
Stable at -20°C for at least 1 year.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Specificity
TGF beta Receptor I (Phospho-Ser165) Antibody detects endogenous levels of TGF beta Receptor I only when phosphorylated at Ser165.
Immunogen
The antiserum was produced against synthesized peptide derived from human TGF beta Receptor I around the phosphorylation site of Ser165.
Properties
If you buy Antibodies supplied by Assay Biotech they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Synonyms
ADRB2; ALK-5; Activin receptor-like kinase 5; ESK2; SKR4; TGF-beta receptor type I precursor; TGF-beta type I receptor; TGF-betaR1; TGFR-1; TGFR1; kinase TGF-beta-R1; receptor R4
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.