Gene ID number
9518
Modification site
None
Conjugation
Cy5.5
Swiss Prot
Q99988
Subcellular location
Secreted
Tested applications
IF(IHC-P)
French translation
anticorps
Modification
Unmodified
Clonality
Polyclonal
Immunogen_range
260-308/308
Target Antigen
GDF15/MIC-1
Excitation Emission
675nm/694nm
Additional conjugation
Cy5.5,Cy5.5
Concentration
1ug per 1ul
Crossreactivity
Human, Mouse, Rat
Recommended dilutions
IF(IHC-P)(1:50-200)
Clone
Polyclonal antibody
Category
Conjugated Primary Antibodies
Host Organism
Rabbit (Oryctolagus cuniculus)
Purification method
This antibody was purified via Protein A.
Long name
GDF15/MIC-1 Polyclonal Antibody, Cy5.5 Conjugated
Specificity
This is a highly specific antibody against GDF15/MIC-1.
Source
KLH conjugated synthetic peptide derived from human GDF-15
Conjugated
These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
Synonyms
PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15; Growth/differentiation factor 15; Macrophage inhibitory cytokine 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; NRG-1; Placental TGF-beta; Placental bone morphogenetic protein; Prostate differentiation factor; GDF15
Antigen background
Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.