TGF beta 1 Antibody, HRP Conjugated

HRP

N/A

7040

None

Human

P01137

Secreted

WB, IHC-P

anticorps

TGF beta 1

Unmodified

Polyclonal

100-150/390

1ug per 1ul

HRP Conjugated

Polyclonal antibody

Conjugated Primary Antibodies

Rabbit (Oryctolagus cuniculus)

WB(1:100-1000), IHC-P(1:100-500)

This antibody was purified via Protein A.

TGF beta 1 Polyclonal Antibody, HRP Conjugated

This is a highly specific antibody against TGF beta 1.

KLH conjugated synthetic peptide derived from human TGF beta 1/LAP

CED; LAP; DPD1; TGFB; TGFbeta; Transforming growth factor beta-1; TGF-beta-1; TGFB1

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.

Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 cells.