Uniprot #
Q12931
Category
Antibody
French translation
anticorps
Conjugation
Unconjugated
Tested applications
WB, IHC, ELISA
Recognised antigen
TRAP-1 (HSP75)
Purity
Antigen affinity
Clone
Polyclonal antibody
Form
Antigen affinity purified
Clonality
Polyclonal (rabbit origin)
Host animal
Rabbit (Oryctolagus cuniculus)
Concentration
In 1X PBS, pH 7.4, with 0.09% sodium azide
Recommended dilutions
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Intented use
This TRAP-1 antibodyis to be used only for research purposes and not for diagnostics..
Immunogen
A portion of amino acids 542-570 from the human protein was used as the immunogen for this TRAP-1 antibody.
Notes
Titration of the TRAP-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Species reactivity
Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
Storage
Aliquot the TRAP-1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
Description
HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. TRAP1 is a mitochondrial HSP90 protein. Other HSP90 proteins are found in cytosol (HSP90AA1) and endoplasmic reticulum (HSP90B1).