Uniprot #

Q12931

Category

Antibody

French translation

anticorps

Conjugation

Unconjugated

Tested applications

WB, IHC, ELISA

Recognised antigen

TRAP-1 (HSP75)

Purity

Antigen affinity

Clone

Polyclonal antibody

Form

Antigen affinity purified

Clonality

Polyclonal (rabbit origin)

Host animal

Rabbit (Oryctolagus cuniculus)

Concentration

In 1X PBS, pH 7.4, with 0.09% sodium azide

Recommended dilutions

Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Intented use

This TRAP-1 antibodyis to be used only for research purposes and not for diagnostics..

Immunogen

A portion of amino acids 542-570 from the human protein was used as the immunogen for this TRAP-1 antibody.

Notes

Titration of the TRAP-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Properties

If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Species reactivity

Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.

Storage

Aliquot the TRAP-1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.

Description

HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. TRAP1 is a mitochondrial HSP90 protein. Other HSP90 proteins are found in cytosol (HSP90AA1) and endoplasmic reticulum (HSP90B1).