Recognised antigen
TGFBI
Uniprot #
Q15582
Category
Antibody
French translation
anticorps
Conjugation
Unconjugated
Tested applications
WB, FACS, ELISA
Purity
Antigen affinity
Clone
Polyclonal antibody
Form
Antigen affinity purified
Clonality
Polyclonal (rabbit origin)
Host animal
Rabbit (Oryctolagus cuniculus)
Concentration
In 1X PBS, pH 7.4, with 0.09% sodium azide
Recommended dilutions
Western blot: 1:1000,Flow Cytometry: 1:10-1:50
Intented use
This TGFBI antibodyis to be used only for research purposes and not for diagnostics..
Immunogen
A portion of amino acids 106-135 from the human protein was used as the immunogen for this TGFBI antibody.
Notes
Titration of the TGFBI antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Species reactivity
Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
Storage
Aliquot the TGFBI antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
Description
Transforming growth factor-beta-induced protein ig-h3 is a RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.