TRAP-1 Antibody / HSP75

Q12931

Antibody

WB, IHC-P

anticorps

Cytoplasmic

Unconjugated

TRAP-1 / HSP75

Antigen affinity

Polyclonal antibody

Antigen affinity purified

Polyclonal (rabbit origin)

Rabbit (Oryctolagus cuniculus)

Western blot: 0.1-0.5ug/ml,IHC (Paraffin): 0.5-1ug/ml

0.5mg/ml if reconstituted with 0.2ml sterile DI water

Optimal dilution of the TRAP1 antibody should be determined by the researcher.

Amino acids 571-704 of human TRAP1 were used as the immunogen for the TRAP1 antibody.

This TRAP1 antibodyis to be used only for research purposes and not for diagnostics..

If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Human (Homo sapiens), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.

After reconstitution, the TRAP1 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.

Heat shock protein 75 kDa, mitochondrial is a protein that in humans is encoded by the TRAP1 gene. It is mapped to 16p13.3. This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. And this protein may function in regulating cellular stress responses. In addition, it was found that TRAP1 interacted with the N-terminal half of TNFR1. Also, TRAP1 interacted with the C-terminal ends of the proteins encoded by both multiple exostoses-causing genes, EXT1 and EXT2, but not with EXTL1 or EXTL3.