NCBI GENE nr

7044

Works with

Human

Ab raised in

Rabbit

Protein nr

O00292

KDa

40 kDa

GENE symbol

LEFTY2

Quantity per ml

1 mg/ml

Omim nr

27436881

Ncbi nr

NP_003231

French translation

anticorps

Type

Polyclonal

Vial with antibody

Lyophilized

Source

Homo sapiens

Antibodie's label

unlabelled serum

Immuno application

ELISA, Western Blot

Antigene name

left-right determination factor 2

Gene names

LEFTY2, EBAF, LEFTA, LEFTYA, MGC46222, TGFB4

Purity

Antibody is purified by peptide affinity chromatography method.

Antigen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LEFTY2.

Suspention, pH, azide

Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.

Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Keep at

For short periods of storage (days) store at 4 grades C. For longer periods of storage, store LEFTY2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.

Antibody advice

LEFTY2 antibody can be used for detection of LEFTY2 by ELISA at 1:312500. LEFTY2 antibody can be used for detection of LEFTY2 by western blot at 1.0 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Gene info

LEFTY2 is a member of the TGF-beta family of proteins. The protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in its gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of its gene in the endometrium.This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.