anti-TGFB1 Antibody

7040

Human

TGFB1

Rabbit

135674

P01137

P01137

anticorps

Polyclonal

in solution

Homo sapiens

unlabelled serum

Immunoaffinity Chromatography

transforming growth factor, beta 1

ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence

0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.

Store TGFB1 antibody at 4 grades C or -20 grades C. As with all antibodies avoid freeze/thaw cycles.

TGFB1 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 ug/mL.

TGFB1 antibody was made against Aa 286-293 (of 390) of full-length (including signal peptide) precursor TGFb protein.

TGFB1, CED, DPD1, Diaphyseal dysplasia 1, LAP, Latency-associated peptide, TGF Beta, TGFbeta, TGF-beta 1 protein, TGF-beta-1, TGFB

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

TGF-β-1 is a multifunctional cytokine that belongs to a superfamily of structurally related regulatory proteins, which includes three mammalian TGF-β isoforms (TGF-β-1, -beta-2, and -beta-3), activin/inhibins and bone morphogenetic proteins. The most abundant isoform, TGF-β-1, is a 25 kDa homodimer composed of two 12.5 kDa subunits joined by disulfide bonds. TGF-β-1 is a highly conserved molecule - the amino acid sequence between human and mouse differ only by one residue. Although originally defined by its ability to cause anchorage independent cell growth and changes in cell morphology of rat fibroblasts, subsequent research has revealed that TGF-β is actually a major growth inhibitor for most cell types. It is produced by a wide variety of cell and tissue types during all stages of cell differentiation. TGF-β-1 sources include platelets, bone and soft tissues such as placenta and kidneys.