Analyses
WB
Entrez GeneID
9518
Target antigen
GDF15
Reacts with species:
human
Gene Name
GDF15
Raised in
rabbit
Uniprot ID
Q99988
French translation
anticorps
Product form
freeze-dried
Clonality
Polyclonal antibody
Clone
Polyclonal antibody
Type of the antibody
IgG polyclonal antibody
Purification
Immunogen affinity purified.
Gene Full Name
growth differentiation factor 15
Protein Name
Growth/differentiation factor 15
Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Synonyms
GDF15 | GDF-15 | GDF 15 | MIC1 | MIC-1 | MIC 1 | NAG1 | NAG-1 | NAG 1 | NRG1 | NRG-1 | NRG 1 | NSAID | PDF | PLAB | PTGF beta | PTGFB | Q99988
Immunogen
E.coli-derived human GDF15 recombinant protein (Position: A195-I308). Human GDF15 shares 68.1% and 69.2% amino acid (aa) sequence identity with mouse and rat GDF15, respectively.
Tips
The GDF15 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
Storage condtions
Keep the GDF15 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
Related articles
1. Hsiao E, Koniaris L, Zimmers-Koniaris T, Sebald S, Huynh T, Lee S (2000). "Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injury". Mol Cell Biol. 20 (10): 3742–3751. 2. Zimmers T, Jin X, Hsiao E, McGrath S, Esquela A, Koniaris L (2005). "Growth differentiation factor-15/macrophage inhibitory cytokine-1 induction after kidney and lung injury". Shock. 23 (6): 543–8.
Background
Growth/differentiation factor 15 (GDF15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF15 is also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB. GDF15 mRNA is most abundant in the liver, with lower levels seen in some other tissues. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung.